Searchable abstracts of presentations at key conferences on calcified tissues

ba0003w4.2 | Endocrine regulation of bone | ECTS2014

Bone sparing glucocorticoids

Cooper Mark

Therapeutic glucocorticoids are still widely used for their anti-inflammatory effects. There are however significant side effects associated with their use. These include effects on bone leading to osteoporosis and fracture but also on muscle (increasing risk of falls) and systemic fuel metabolism (leading to diabetes and increased cardiovascular risk). Research over many decades has tried to develop agents which retain the anti-inflammatory effects of glucocorticoids but have...